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	<title>Comments on: Five For Fridays &#8211; Mar 13, 2009</title>
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		<title>By: Ayala Laufer-Cahana M.D.</title>
		<link>http://www.littlestomaks.com/2009/03/five-for-fridays-mar-13-2009/#comment-232</link>
		<dc:creator>Ayala Laufer-Cahana M.D.</dc:creator>
		<pubDate>Fri, 13 Mar 2009 14:05:40 +0000</pubDate>
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		<description>Great post!

You&#039;re brave to tackle the vitamin D issue.  I am both intrigued and confused by the proliferation of studies finding low vitamin D in practically every disease process, from cancer to heart disease to obesity.

The questions are:

1.	Is the low vitamin D a part of the cause of the disease, or a manifestation of an unhealthy state, i.e. just a marker of disease.  It would be similar to blaming a fever for the inflammation of the ear or lungs during an infectious disease.  Vitamin D metabolism is complicated, therefore low vitamin D can be a result of both unhealthy lifestyle (engaging in less physical activity, which could be related to less sun exposure and eating an unhealthy diet), but also a sign that some of the many body systems (skin, kidney, liver) that participate in vitamin D production aren&#039;t functioning well.

2.	Can supplementation with vitamin D improve those conditions associated with low vitamin D? This question needs to be addressed in a large randomized clinical trial of vitamin D supplementation.  Other vitamins were thought to be protective against disease and trails proved that not to be the case.

At this point, all we know is that low vitamin D has been correlated with many states of disease.  We don’t know it’s a cause.  We don’t know if supplementation will lead to a better outcome.

That&#039;s for sure Vitamin D is a hot topic!</description>
		<content:encoded><![CDATA[<p>Great post!</p>
<p>You&#8217;re brave to tackle the vitamin D issue.  I am both intrigued and confused by the proliferation of studies finding low vitamin D in practically every disease process, from cancer to heart disease to obesity.</p>
<p>The questions are:</p>
<p>1.	Is the low vitamin D a part of the cause of the disease, or a manifestation of an unhealthy state, i.e. just a marker of disease.  It would be similar to blaming a fever for the inflammation of the ear or lungs during an infectious disease.  Vitamin D metabolism is complicated, therefore low vitamin D can be a result of both unhealthy lifestyle (engaging in less physical activity, which could be related to less sun exposure and eating an unhealthy diet), but also a sign that some of the many body systems (skin, kidney, liver) that participate in vitamin D production aren&#8217;t functioning well.</p>
<p>2.	Can supplementation with vitamin D improve those conditions associated with low vitamin D? This question needs to be addressed in a large randomized clinical trial of vitamin D supplementation.  Other vitamins were thought to be protective against disease and trails proved that not to be the case.</p>
<p>At this point, all we know is that low vitamin D has been correlated with many states of disease.  We don’t know it’s a cause.  We don’t know if supplementation will lead to a better outcome.</p>
<p>That&#8217;s for sure Vitamin D is a hot topic!</p>
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		<title>By: Ayala Laufer-Cahana M.D.</title>
		<link>http://www.littlestomaks.com/2009/03/five-for-fridays-mar-13-2009/#comment-2964</link>
		<dc:creator>Ayala Laufer-Cahana M.D.</dc:creator>
		<pubDate>Fri, 13 Mar 2009 14:05:00 +0000</pubDate>
		<guid isPermaLink="false">http://www.littlestomaks.com/?p=1179#comment-2964</guid>
		<description>Great post!

You&#039;re brave to tackle the vitamin D issue.  I am both intrigued and confused by the proliferation of studies finding low vitamin D in practically every disease process, from cancer to heart disease to obesity.

The questions are:

1.	Is the low vitamin D a part of the cause of the disease, or a manifestation of an unhealthy state, i.e. just a marker of disease.  It would be similar to blaming a fever for the inflammation of the ear or lungs during an infectious disease.  Vitamin D metabolism is complicated, therefore low vitamin D can be a result of both unhealthy lifestyle (engaging in less physical activity, which could be related to less sun exposure and eating an unhealthy diet), but also a sign that some of the many body systems (skin, kidney, liver) that participate in vitamin D production aren&#039;t functioning well.

2.	Can supplementation with vitamin D improve those conditions associated with low vitamin D? This question needs to be addressed in a large randomized clinical trial of vitamin D supplementation.  Other vitamins were thought to be protective against disease and trails proved that not to be the case.

At this point, all we know is that low vitamin D has been correlated with many states of disease.  We don’t know it’s a cause.  We don’t know if supplementation will lead to a better outcome.

That&#039;s for sure Vitamin D is a hot topic!</description>
		<content:encoded><![CDATA[<p>Great post!</p>
<p>You&#8217;re brave to tackle the vitamin D issue.  I am both intrigued and confused by the proliferation of studies finding low vitamin D in practically every disease process, from cancer to heart disease to obesity.</p>
<p>The questions are:</p>
<p>1.	Is the low vitamin D a part of the cause of the disease, or a manifestation of an unhealthy state, i.e. just a marker of disease.  It would be similar to blaming a fever for the inflammation of the ear or lungs during an infectious disease.  Vitamin D metabolism is complicated, therefore low vitamin D can be a result of both unhealthy lifestyle (engaging in less physical activity, which could be related to less sun exposure and eating an unhealthy diet), but also a sign that some of the many body systems (skin, kidney, liver) that participate in vitamin D production aren&#8217;t functioning well.</p>
<p>2.	Can supplementation with vitamin D improve those conditions associated with low vitamin D? This question needs to be addressed in a large randomized clinical trial of vitamin D supplementation.  Other vitamins were thought to be protective against disease and trails proved that not to be the case.</p>
<p>At this point, all we know is that low vitamin D has been correlated with many states of disease.  We don’t know it’s a cause.  We don’t know if supplementation will lead to a better outcome.</p>
<p>That&#8217;s for sure Vitamin D is a hot topic!</p>
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